The Biobase BSC-1100IIB2-X is a specialized Class II B2 biological safety cabinet designed for the safe handling of hazardous biological materials that are also treated with volatile toxic chemicals or radionuclides. Unlike A2 cabinets, the B2-X series features a “Total Exhaust” design, where 100% of the HEPA-filtered air is exhausted through a dedicated ducting system to the outside, with zero air recirculation back into the work zone. This makes it the only safe choice for applications involving both biological and chemical hazards where any recirculated fumes could pose a risk to the operator or the sample. The unit is equipped with high-precision pressure sensors and an interlocked exhaust system that prevents operation if airflow is compromised. Built with a rugged 304 stainless steel interior and a motorized tempered glass sash, the BSC-1100IIB2-X provides the specialized, uncompromised safety required for oncology research, chemical-biological testing, and advanced pharmacology.